Drug interactions
Indacaterol-glycopyrronium + Scopolamine
Severity: Moderate
Indacaterol-glycopyrronium and Scopolamine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents are muscarinic antagonists, so combining them may add to anticholinergic effects such as dry mouth, blurred vision, urinary retention and confusion. Systemic scopolamine, especially in older adults, may increase this risk.
What this interaction means in plain words
Indacaterol-glycopyrronium and Scopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol-glycopyrronium belongs to Respiratory; Scopolamine belongs to Respiratory.
Why it happens
Additive muscarinic receptor blockade.
What to do
Monitor for anticholinergic adverse effects, particularly in older patients or those with glaucoma or urinary retention. Reduce or stop one agent if symptoms occur.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Scopolamine
Frequently asked questions
Can I take Indacaterol-glycopyrronium with Scopolamine?
MediHelp rates the interaction as moderate. Indacaterol-glycopyrronium and Scopolamine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents are muscarinic antagonists, so combining them may add to anticholinergic effects such as dry mouth, blurred vision, urinary retention and confusion. Systemic scopolamine, especially in older adults, may increase this risk.
How serious is the interaction between Indacaterol-glycopyrronium and Scopolamine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic adverse effects, particularly in older patients or those with glaucoma or urinary retention. Reduce or stop one agent if symptoms occur.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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