Drug interactions
Indacaterol-glycopyrronium + Sunitinib
Severity: Moderate
Indacaterol-glycopyrronium and Sunitinib: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Sunitinib can prolong the QT interval, and beta2-agonists such as indacaterol may add to this effect, especially through hypokalemia or at high doses. The clinical risk with standard inhaled dosing is likely small but matters in patients with other risk factors.
What this interaction means in plain words
Indacaterol-glycopyrronium and Sunitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol-glycopyrronium belongs to Respiratory; Sunitinib belongs to Oncology.
Why it happens
Additive QT prolongation through different mechanisms.
What to do
Check baseline ECG and electrolytes in patients with QT risk factors. Correct potassium and magnesium abnormalities and monitor periodically.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Sunitinib
- Adagrasib + Sunitinib Major
- Amiodarone + Sunitinib Major
- Amisulpride + Sunitinib Major
- Anagrelide + Sunitinib Major
- Apalutamide + Sunitinib Major
- Arsenic trioxide + Sunitinib Major
Frequently asked questions
Can I take Indacaterol-glycopyrronium with Sunitinib?
MediHelp rates the interaction as moderate. Indacaterol-glycopyrronium and Sunitinib can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sunitinib can prolong the QT interval, and beta2-agonists such as indacaterol may add to this effect, especially through hypokalemia or at high doses. The clinical risk with standard inhaled dosing is likely small but matters in patients with other risk factors.
How serious is the interaction between Indacaterol-glycopyrronium and Sunitinib?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check baseline ECG and electrolytes in patients with QT risk factors. Correct potassium and magnesium abnormalities and monitor periodically.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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