Drug interactions
Indacaterol-glycopyrronium + Telavancin
Severity: Moderate
Indacaterol-glycopyrronium and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Telavancin has been associated with QT prolongation, and indacaterol may add to cardiac repolarization effects, particularly if hypokalemia develops. The combination may increase the risk of ventricular arrhythmia in susceptible patients.
What this interaction means in plain words
Indacaterol-glycopyrronium and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol-glycopyrronium belongs to Respiratory; Telavancin belongs to Anti Bacterial.
Why it happens
Additive QT prolongation and beta2-mediated hypokalemia.
What to do
Obtain a baseline ECG in patients with QT risk factors and keep potassium and magnesium in the normal range during telavancin therapy.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Frequently asked questions
Can I take Indacaterol-glycopyrronium with Telavancin?
MediHelp rates the interaction as moderate. Indacaterol-glycopyrronium and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Telavancin has been associated with QT prolongation, and indacaterol may add to cardiac repolarization effects, particularly if hypokalemia develops. The combination may increase the risk of ventricular arrhythmia in susceptible patients.
How serious is the interaction between Indacaterol-glycopyrronium and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG in patients with QT risk factors and keep potassium and magnesium in the normal range during telavancin therapy.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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