Drug interactions
Indacaterol inhaled + Methylprednisolone
Severity: Moderate
Indacaterol inhaled and Methylprednisolone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both corticosteroids and beta-2 agonists lower serum potassium. Together they may cause additive hypokalemia, with a risk of arrhythmia in susceptible patients.
What this interaction means in plain words
Indacaterol inhaled and Methylprednisolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive potassium lowering through beta-2 mediated intracellular shift and corticosteroid mineralocorticoid-related renal potassium loss.
What to do
Monitor serum potassium in patients on high-dose steroids, especially with other hypokalemic drugs, and replace potassium as needed.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Methylprednisolone
- Bcg vaccine live + Methylprednisolone Contraindicated
- Measles mumps and rubella vaccine live + Methylprednisolone Contraindicated
- Measles mumps rubella and varicella vaccine live + Methylprednisolone Contraindicated
- Measles vaccine + Methylprednisolone Contraindicated
- Methylprednisolone + Mifepristone Contraindicated
- Methylprednisolone + Rubella vaccine Contraindicated
Frequently asked questions
Can I take Indacaterol inhaled with Methylprednisolone?
MediHelp rates the interaction as moderate. Indacaterol inhaled and Methylprednisolone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both corticosteroids and beta-2 agonists lower serum potassium. Together they may cause additive hypokalemia, with a risk of arrhythmia in susceptible patients.
How serious is the interaction between Indacaterol inhaled and Methylprednisolone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium in patients on high-dose steroids, especially with other hypokalemic drugs, and replace potassium as needed.
What other medicines interact with Methylprednisolone?
MediHelp also lists interactions of Methylprednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Methylprednisolone page.
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