Drug reference
methylprednisolone
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Endocrine (Adrenocortical Drugs)
Mechanism of action
It acts in various ways to decrease the inflammatory cycle including: dampening the inflammatory cytokine cascade, inhibiting the activation of T cells, decreasing the extravasation of immune cells into the central nervous system, facilitating the apoptosis of activated immune cells.
Common side effects
- Swelling of your ankles, feet, or hands
- Weight gain
- Menstrual irregularity
- Mild muscle pain or weakness
Contraindications
- Untreated serious infections Documented hypersensitivity to drug or components (eg, lactose monohydrate from cow milk) Intrathecal administration Systemic fungal infection (except intra-articular injection in localized joint conditions) IM route is contraindicated in idiopathic thromboc…
Known interactions (2)
Related conditions
Frequently asked questions
What drug class is methylprednisolone?
methylprednisolone belongs to: Endocrine.
How does methylprednisolone work?
It acts in various ways to decrease the inflammatory cycle including: dampening the inflammatory cytokine cascade, inhibiting the activation of T cells, decreasing the extravasation of immune cells into the central nervous system, facilitating the apoptosis of activated immune cells.
What are the common side effects of methylprednisolone?
Swelling of your ankles, feet, or hands, Weight gain, Menstrual irregularity, Mild muscle pain or weakness
Which drugs interact with methylprednisolone?
hepatitis a vaccine inactivated, terbutaline
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.