Drug interactions
Infliximab + Meningococcal a c y and w-135 polysaccharide vaccine combined
Severity: Minor
Infliximab and Meningococcal a c y and w-135 polysaccharide vaccine combined: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
This is a non-live vaccine, so there is no risk of vaccine-strain infection. Infliximab may reduce the antibody response, though vaccination is still recommended.
What this interaction means in plain words
Infliximab and Meningococcal a c y and w-135 polysaccharide vaccine combined have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
TNF blockade-related immunosuppression may modestly reduce vaccine antibody responses.
What to do
Vaccinate as indicated, preferably before starting infliximab. Do not withhold infliximab for the vaccination.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Infliximab
- Bcg vaccine live + Infliximab Contraindicated
- Infliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Infliximab + Measles mumps and rubella vaccine Contraindicated
- Infliximab + Measles mumps and rubella vaccine live Contraindicated
- Infliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Infliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Infliximab with Meningococcal a c y and w-135 polysaccharide vaccine combined?
MediHelp rates the interaction as minor. Infliximab and Meningococcal a c y and w-135 polysaccharide vaccine combined have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. This is a non-live vaccine, so there is no risk of vaccine-strain infection. Infliximab may reduce the antibody response, though vaccination is still recommended.
How serious is the interaction between Infliximab and Meningococcal a c y and w-135 polysaccharide vaccine combined?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate as indicated, preferably before starting infliximab. Do not withhold infliximab for the vaccination.
What other medicines interact with Infliximab?
MediHelp also lists interactions of Infliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Infliximab page.
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