Drug interactions
Infliximab + Poliovirus vaccine inactivated
Severity: Minor
Infliximab and Poliovirus vaccine inactivated: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Infliximab may lower the antibody response to inactivated poliovirus vaccine. The vaccine is not live and is safe to give, but protection may be reduced.
What this interaction means in plain words
Infliximab and Poliovirus vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
TNF-alpha blockade attenuates the immune response to vaccine antigens.
What to do
Give inactivated vaccines before starting infliximab where possible, and do not withhold them if therapy is already underway. Consider checking titers or revaccinating if protection is critical.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Infliximab
- Bcg vaccine live + Infliximab Contraindicated
- Infliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Infliximab + Measles mumps and rubella vaccine Contraindicated
- Infliximab + Measles mumps and rubella vaccine live Contraindicated
- Infliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Infliximab + Measles vaccine Contraindicated
Frequently asked questions
Can I take Infliximab with Poliovirus vaccine inactivated?
MediHelp rates the interaction as minor. Infliximab and Poliovirus vaccine inactivated have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Infliximab may lower the antibody response to inactivated poliovirus vaccine. The vaccine is not live and is safe to give, but protection may be reduced.
How serious is the interaction between Infliximab and Poliovirus vaccine inactivated?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give inactivated vaccines before starting infliximab where possible, and do not withhold them if therapy is already underway. Consider checking titers or revaccinating if protection is critical.
What other medicines interact with Infliximab?
MediHelp also lists interactions of Infliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Infliximab page.
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