Drug interactions
Infliximab + Valoctocogene roxaparvovec
Severity: Moderate
Infliximab and Valoctocogene roxaparvovec: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Valoctocogene roxaparvovec frequently raises liver enzymes, and infliximab can rarely cause liver injury. Together they may increase hepatotoxicity risk and affect gene expression.
What this interaction means in plain words
Infliximab and Valoctocogene roxaparvovec can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Infliximab belongs to Musculoskeletal; Valoctocogene roxaparvovec belongs to Miscellaneous.
Why it happens
Additive hepatotoxic potential.
What to do
Monitor ALT and other liver tests regularly after gene therapy. Evaluate all hepatotoxic drugs if enzymes rise.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Infliximab
- Bcg vaccine live + Infliximab Contraindicated
- Infliximab + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Infliximab + Measles mumps and rubella vaccine Contraindicated
- Infliximab + Measles mumps and rubella vaccine live Contraindicated
- Infliximab + Measles mumps rubella and varicella vaccine live Contraindicated
- Infliximab + Measles vaccine Contraindicated
Other interactions of Valoctocogene roxaparvovec
Frequently asked questions
Can I take Infliximab with Valoctocogene roxaparvovec?
MediHelp rates the interaction as moderate. Infliximab and Valoctocogene roxaparvovec can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Valoctocogene roxaparvovec frequently raises liver enzymes, and infliximab can rarely cause liver injury. Together they may increase hepatotoxicity risk and affect gene expression.
How serious is the interaction between Infliximab and Valoctocogene roxaparvovec?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ALT and other liver tests regularly after gene therapy. Evaluate all hepatotoxic drugs if enzymes rise.
What other medicines interact with Infliximab?
MediHelp also lists interactions of Infliximab with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine. The full list is on the Infliximab page.
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