Drug interactions
Insulin degludec-insulin aspart + Magnesium salicylate
Severity: Moderate
Insulin degludec-insulin aspart and Magnesium salicylate: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Salicylates at higher doses can lower blood glucose and may add to the effect of insulin. This can increase the risk of hypoglycemia, especially with regular or high-dose salicylate use.
What this interaction means in plain words
Insulin degludec-insulin aspart and Magnesium salicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Additive glucose-lowering effect; salicylates may enhance insulin secretion and sensitivity.
What to do
Monitor blood glucose when salicylate is started, stopped or used regularly at high doses. Reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin degludec-insulin aspart
- Chlorpropamide + Insulin degludec-insulin aspart Major
- Clozapine + Insulin degludec-insulin aspart Major
- Diazoxide + Insulin degludec-insulin aspart Major
- Ethanol + Insulin degludec-insulin aspart Major
- Insulin degludec-insulin aspart + Mecasermin Major
- Insulin degludec-insulin aspart + Pioglitazone Major
Frequently asked questions
Can I take Insulin degludec-insulin aspart with Magnesium salicylate?
MediHelp rates the interaction as moderate. Insulin degludec-insulin aspart and Magnesium salicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Salicylates at higher doses can lower blood glucose and may add to the effect of insulin. This can increase the risk of hypoglycemia, especially with regular or high-dose salicylate use.
How serious is the interaction between Insulin degludec-insulin aspart and Magnesium salicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when salicylate is started, stopped or used regularly at high doses. Reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
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