Drug interactions
Insulin degludec-insulin aspart + Triamcinolone acetonide injectable
Severity: Moderate
Insulin degludec-insulin aspart and Triamcinolone acetonide injectable: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Injected corticosteroids can cause hyperglycemia lasting days to weeks and may substantially raise insulin requirements. Poor glycemic control or hyperglycemic crises can follow if doses are not adjusted.
What this interaction means in plain words
Insulin degludec-insulin aspart and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Corticosteroids increase insulin resistance and hepatic glucose production, antagonizing insulin.
What to do
Check blood glucose more often for several days to weeks after the injection and increase insulin as needed. Reduce insulin again as the steroid effect wanes.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin degludec-insulin aspart
- Chlorpropamide + Insulin degludec-insulin aspart Major
- Clozapine + Insulin degludec-insulin aspart Major
- Diazoxide + Insulin degludec-insulin aspart Major
- Ethanol + Insulin degludec-insulin aspart Major
- Insulin degludec-insulin aspart + Mecasermin Major
- Insulin degludec-insulin aspart + Pioglitazone Major
Frequently asked questions
Can I take Insulin degludec-insulin aspart with Triamcinolone acetonide injectable?
MediHelp rates the interaction as moderate. Insulin degludec-insulin aspart and Triamcinolone acetonide injectable can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Injected corticosteroids can cause hyperglycemia lasting days to weeks and may substantially raise insulin requirements. Poor glycemic control or hyperglycemic crises can follow if doses are not adjusted.
How serious is the interaction between Insulin degludec-insulin aspart and Triamcinolone acetonide injectable?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check blood glucose more often for several days to weeks after the injection and increase insulin as needed. Reduce insulin again as the steroid effect wanes.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
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