Drug interactions
Insulin degludec-liraglutide + Losartan
Severity: Minor
Insulin degludec-liraglutide and Losartan: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Angiotensin receptor blockers may improve insulin sensitivity and can slightly increase the hypoglycemic effect of insulin. Hypoglycemia is uncommon but possible, especially when the ARB is newly started.
What this interaction means in plain words
Insulin degludec-liraglutide and Losartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Insulin degludec-liraglutide belongs to Endocrine; Losartan belongs to Cardiovascular.
Why it happens
ARBs may improve insulin sensitivity, adding to the glucose-lowering effect of insulin and liraglutide.
What to do
Monitor blood glucose after starting losartan and reduce the insulin dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Insulin degludec-liraglutide
Other interactions of Losartan
- Aliskiren + Losartan Contraindicated
- Losartan + Sparsentan Contraindicated
- Amifostine + Losartan Major
- Amiloride + Losartan Major
- Amlodipine-benazepril + Losartan Major
- Amlodipine-hydrochlorothiazide-valsartan + Losartan Major
Frequently asked questions
Can I take Insulin degludec-liraglutide with Losartan?
MediHelp rates the interaction as minor. Insulin degludec-liraglutide and Losartan have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Angiotensin receptor blockers may improve insulin sensitivity and can slightly increase the hypoglycemic effect of insulin. Hypoglycemia is uncommon but possible, especially when the ARB is newly started.
How serious is the interaction between Insulin degludec-liraglutide and Losartan?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting losartan and reduce the insulin dose if hypoglycemia occurs.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
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