Drug interactions
Insulin glargine + Somatrogon
Severity: Moderate
Insulin glargine and Somatrogon: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Somatrogon may reduce insulin sensitivity and raise glucose, so patients on insulin glargine may need dose increases.
What this interaction means in plain words
Insulin glargine and Somatrogon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Insulin glargine belongs to Endocrine; Somatrogon belongs to Endocrine.
Why it happens
Growth hormone induces insulin resistance, antagonizing insulin's glucose-lowering effect.
What to do
Monitor glucose more often after starting somatrogon or changing its dose and titrate insulin accordingly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Insulin glargine
Other interactions of Somatrogon
- Alogliptin-metformin + Somatrogon Moderate
- Alogliptin-pioglitazone + Somatrogon Moderate
- Alogliptin + Somatrogon Moderate
- Canagliflozin-metformin + Somatrogon Moderate
- Chlorpropamide + Somatrogon Moderate
- Cyclosporin + Somatrogon Moderate
Frequently asked questions
Can I take Insulin glargine with Somatrogon?
MediHelp rates the interaction as moderate. Insulin glargine and Somatrogon can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Somatrogon may reduce insulin sensitivity and raise glucose, so patients on insulin glargine may need dose increases.
How serious is the interaction between Insulin glargine and Somatrogon?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glucose more often after starting somatrogon or changing its dose and titrate insulin accordingly.
What other medicines interact with Insulin glargine?
MediHelp also lists interactions of Insulin glargine with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin glargine page.
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