Drug interactions
Interferon beta 1b + Ozanimod
Severity: Moderate
Interferon beta 1b and Ozanimod: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ozanimod reduces circulating lymphocytes and interferon beta 1b has immunomodulatory effects, so combining them may increase infection risk. Ozanimod's effect on lymphocytes persists after discontinuation.
What this interaction means in plain words
Interferon beta 1b and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Interferon beta 1b belongs to Central Nervous System; Ozanimod belongs to Central Nervous System.
Why it happens
Additive immunomodulation through lymphocyte sequestration and interferon effects.
What to do
Do not use together routinely; when switching, stop interferon first and monitor for infection. Check a recent complete blood count including lymphocytes before starting ozanimod.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Interferon beta 1b and Ozanimod, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Interferon beta 1b
Other interactions of Ozanimod
- Isocarboxazid + Ozanimod Contraindicated
- Linezolid + Ozanimod Contraindicated
- Ozanimod + Phenelzine Contraindicated
- Ozanimod + Procarbazine Contraindicated
- Ozanimod + Rasagiline Contraindicated
- Ozanimod + Safinamide Contraindicated
Frequently asked questions
Can I take Interferon beta 1b with Ozanimod?
MediHelp rates the interaction as moderate. Interferon beta 1b and Ozanimod can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Ozanimod reduces circulating lymphocytes and interferon beta 1b has immunomodulatory effects, so combining them may increase infection risk. Ozanimod's effect on lymphocytes persists after discontinuation.
How serious is the interaction between Interferon beta 1b and Ozanimod?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together routinely; when switching, stop interferon first and monitor for infection. Check a recent complete blood count including lymphocytes before starting ozanimod.
What other medicines interact with Interferon beta 1b?
MediHelp also lists interactions of Interferon beta 1b with, for example, Axicabtagene ciloleucel, Brexucabtagene autoleucel, Ciltacabtagene autoleucel. The full list is on the Interferon beta 1b page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
