Drug interactions
Ipratropium-salbutamol + Quetiapine
Severity: Moderate
Ipratropium-salbutamol and Quetiapine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quetiapine can prolong QT and has anticholinergic and sedative effects, and high-dose salbutamol may add to QT risk via hypokalemia and tachycardia. The anticholinergic contribution of inhaled ipratropium is small.
What this interaction means in plain words
Ipratropium-salbutamol and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ipratropium-salbutamol belongs to Respiratory; Quetiapine belongs to Central Nervous System.
Why it happens
Additive QT prolongation, with beta-agonist-induced hypokalemia and weak additive anticholinergic effects.
What to do
Check ECG and electrolytes in patients with other QT risk factors, and avoid excessive salbutamol dosing.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ipratropium-salbutamol
Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Frequently asked questions
Can I take Ipratropium-salbutamol with Quetiapine?
MediHelp rates the interaction as moderate. Ipratropium-salbutamol and Quetiapine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Quetiapine can prolong QT and has anticholinergic and sedative effects, and high-dose salbutamol may add to QT risk via hypokalemia and tachycardia. The anticholinergic contribution of inhaled ipratropium is small.
How serious is the interaction between Ipratropium-salbutamol and Quetiapine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check ECG and electrolytes in patients with other QT risk factors, and avoid excessive salbutamol dosing.
What other medicines interact with Ipratropium-salbutamol?
MediHelp also lists interactions of Ipratropium-salbutamol with, for example, Amisulpride, Arsenic trioxide, Carvedilol. The full list is on the Ipratropium-salbutamol page.
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