Drug interactions
Itraconazole + Telavancin
Severity: Moderate
Itraconazole and Telavancin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Itraconazole can prolong the QT interval and telavancin has been linked to QTc prolongation. Combining them may produce additive effects on cardiac repolarization and raise arrhythmia risk.
What this interaction means in plain words
Itraconazole and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Itraconazole belongs to Anti Fungals; Telavancin belongs to Anti Bacterial.
Why it happens
Additive pharmacodynamic QTc prolongation.
What to do
Obtain a baseline ECG and electrolytes, then monitor the QTc during concurrent therapy. Avoid adding further QT-prolonging drugs and consider an alternative antifungal in high-risk patients.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Itraconazole
- Alfuzosin + Itraconazole Contraindicated
- Alprazolam + Itraconazole Contraindicated
- Avanafil + Itraconazole Contraindicated
- Conivaptan + Itraconazole Contraindicated
- Dihydroergotamine intranasal + Itraconazole Contraindicated
- Dihydroergotamine + Itraconazole Contraindicated
Frequently asked questions
Can I take Itraconazole with Telavancin?
MediHelp rates the interaction as moderate. Itraconazole and Telavancin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Itraconazole can prolong the QT interval and telavancin has been linked to QTc prolongation. Combining them may produce additive effects on cardiac repolarization and raise arrhythmia risk.
How serious is the interaction between Itraconazole and Telavancin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and electrolytes, then monitor the QTc during concurrent therapy. Avoid adding further QT-prolonging drugs and consider an alternative antifungal in high-risk patients.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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