Drug interactions
Ketorolac + Travoprost
Severity: Minor
Ketorolac and Travoprost: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Evidence of an interaction between NSAIDs and ophthalmic prostaglandin analogues is conflicting. Some reports suggest a reduced intraocular pressure lowering effect, while others suggest no effect or the opposite.
What this interaction means in plain words
Ketorolac and Travoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ketorolac belongs to Musculoskeletal; Travoprost belongs to Miscellaneous.
Why it happens
NSAIDs inhibit prostaglandin synthesis, which could theoretically alter the uveoscleral outflow response to travoprost; the effect is not established.
What to do
No routine action is needed; check intraocular pressure if control appears to change after starting ketorolac.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ketorolac
- Aceclofenac + Ketorolac Contraindicated
- Acemetacin + Ketorolac Contraindicated
- Acetylsalicylic acid + Ketorolac Contraindicated
- Apixaban + Ketorolac Contraindicated
- Argatroban + Ketorolac Contraindicated
- Aspirin / citric acid / sodium bicarbonate + Ketorolac Contraindicated
Other interactions of Travoprost
- Bimatoprost + Travoprost Moderate
- Latanoprostene bunod + Travoprost Moderate
- Latanoprost + Travoprost Moderate
- Tafluprost + Travoprost Moderate
- Celecoxib + Travoprost Minor
- Diclofenac + Travoprost Minor
Frequently asked questions
Can I take Ketorolac with Travoprost?
MediHelp rates the interaction as minor. Ketorolac and Travoprost have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Evidence of an interaction between NSAIDs and ophthalmic prostaglandin analogues is conflicting. Some reports suggest a reduced intraocular pressure lowering effect, while others suggest no effect or the opposite.
How serious is the interaction between Ketorolac and Travoprost?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine action is needed; check intraocular pressure if control appears to change after starting ketorolac.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
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