Drug interactions
Lasmiditan + Timolol
Severity: Minor
Lasmiditan and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan can lower heart rate, and with a beta-blocker the reduction is greater than with the beta-blocker alone. This may lead to symptomatic bradycardia in susceptible patients.
What this interaction means in plain words
Lasmiditan and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lasmiditan belongs to Central Nervous System; Timolol belongs to Cardiovascular.
Why it happens
Additive heart rate lowering through pharmacodynamic synergism.
What to do
Monitor heart rate and symptoms of bradycardia such as dizziness or syncope when lasmiditan is used in patients taking timolol.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Timolol
- Acebutolol + Timolol Major
- Albuterol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Lasmiditan with Timolol?
MediHelp rates the interaction as minor. Lasmiditan and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lasmiditan can lower heart rate, and with a beta-blocker the reduction is greater than with the beta-blocker alone. This may lead to symptomatic bradycardia in susceptible patients.
How serious is the interaction between Lasmiditan and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and symptoms of bradycardia such as dizziness or syncope when lasmiditan is used in patients taking timolol.
What other medicines interact with Timolol?
MediHelp also lists interactions of Timolol with, for example, Acebutolol, Albuterol, Aldesleukin. The full list is on the Timolol page.
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