Drug interactions
Lemborexant + Vinblastine
Severity: Minor
Lemborexant and Vinblastine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Vinblastine is not an established CYP3A4 inhibitor, so a meaningful increase in lemborexant exposure is unlikely. Any effect would be additive somnolence.
What this interaction means in plain words
Lemborexant and Vinblastine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lemborexant belongs to Central Nervous System; Vinblastine belongs to Oncology.
Why it happens
Theoretical weak CYP3A4 competition; not established.
What to do
No dose change is needed. Counsel on daytime drowsiness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Lemborexant and Vinblastine, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Vinblastine
Other interactions of Lemborexant
Frequently asked questions
Can I take Lemborexant with Vinblastine?
MediHelp rates the interaction as minor. Lemborexant and Vinblastine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Vinblastine is not an established CYP3A4 inhibitor, so a meaningful increase in lemborexant exposure is unlikely. Any effect would be additive somnolence.
How serious is the interaction between Lemborexant and Vinblastine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose change is needed. Counsel on daytime drowsiness.
What other medicines interact with Vinblastine?
MediHelp also lists interactions of Vinblastine with, for example, Adenovirus types 4 and 7 live, Apalutamide, Atazanavir. The full list is on the Vinblastine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
