Drug interactions
Lenvatinib + Salbutamol
Severity: Moderate
Lenvatinib and Salbutamol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lenvatinib is associated with QT prolongation, and salbutamol may further increase risk, especially if potassium falls. Lenvatinib also causes hypertension and electrolyte disturbances that may compound the concern.
What this interaction means in plain words
Lenvatinib and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Lenvatinib belongs to Oncology; Salbutamol belongs to Respiratory.
Why it happens
Additive QT prolongation, with beta-agonist hypokalemia as a possible contributor.
What to do
Monitor ECG, potassium, magnesium and calcium during co-administration, and correct abnormalities promptly.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Salbutamol
Other interactions of Lenvatinib
- Amiodarone + Lenvatinib Major
- Amisulpride + Lenvatinib Major
- Asenapine + Lenvatinib Major
- Chlorpromazine + Lenvatinib Major
- Donepezil + Lenvatinib Major
- Haloperidol + Lenvatinib Major
Frequently asked questions
Can I take Lenvatinib with Salbutamol?
MediHelp rates the interaction as moderate. Lenvatinib and Salbutamol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lenvatinib is associated with QT prolongation, and salbutamol may further increase risk, especially if potassium falls. Lenvatinib also causes hypertension and electrolyte disturbances that may compound the concern.
How serious is the interaction between Lenvatinib and Salbutamol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor ECG, potassium, magnesium and calcium during co-administration, and correct abnormalities promptly.
What other medicines interact with Salbutamol?
MediHelp also lists interactions of Salbutamol with, for example, Arsenic trioxide, Carvedilol, Droperidol. The full list is on the Salbutamol page.
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