Drug interactions
Levetiracetam + Quetiapine
Severity: Minor
Levetiracetam and Quetiapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both drugs depress the central nervous system, so taking them together can increase drowsiness, dizziness and impaired psychomotor performance. The effect is usually modest but matters for driving, falls and older patients.
What this interaction means in plain words
Levetiracetam and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Levetiracetam belongs to Central Nervous System; Quetiapine belongs to Central Nervous System.
Why it happens
Additive CNS depressant effects; no significant pharmacokinetic interaction is expected.
What to do
Counsel the patient about additive sedation and advise against driving until the response is known. Reduce doses if excessive somnolence develops, especially in elderly patients.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Quetiapine
- Adagrasib + Quetiapine Major
- Amiodarone + Quetiapine Major
- Amisulpride + Quetiapine Major
- Amoxapine + Quetiapine Major
- Anagrelide + Quetiapine Major
- Apalutamide + Quetiapine Major
Other interactions of Levetiracetam
Frequently asked questions
Can I take Levetiracetam with Quetiapine?
MediHelp rates the interaction as minor. Levetiracetam and Quetiapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both drugs depress the central nervous system, so taking them together can increase drowsiness, dizziness and impaired psychomotor performance. The effect is usually modest but matters for driving, falls and older patients.
How serious is the interaction between Levetiracetam and Quetiapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient about additive sedation and advise against driving until the response is known. Reduce doses if excessive somnolence develops, especially in elderly patients.
What other medicines interact with Quetiapine?
MediHelp also lists interactions of Quetiapine with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Quetiapine page.
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