Drug interactions
Levocetirizine + Methohexital
Severity: Moderate
Levocetirizine and Methohexital: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Methohexital is a barbiturate anesthetic, and levocetirizine can add to sedation and prolong recovery. Anesthetic requirements and recovery time may be affected.
What this interaction means in plain words
Levocetirizine and Methohexital can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levocetirizine belongs to Respiratory; Methohexital belongs to Central Nervous System.
Why it happens
Additive CNS depression (pharmacodynamic).
What to do
Titrate methohexital carefully and monitor sedation, airway and recovery in patients taking antihistamines.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levocetirizine
Other interactions of Methohexital
Frequently asked questions
Can I take Levocetirizine with Methohexital?
MediHelp rates the interaction as moderate. Levocetirizine and Methohexital can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Methohexital is a barbiturate anesthetic, and levocetirizine can add to sedation and prolong recovery. Anesthetic requirements and recovery time may be affected.
How serious is the interaction between Levocetirizine and Methohexital?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Titrate methohexital carefully and monitor sedation, airway and recovery in patients taking antihistamines.
What other medicines interact with Levocetirizine?
MediHelp also lists interactions of Levocetirizine with, for example, Acrivastine, Asenapine transdermal, Avapritinib. The full list is on the Levocetirizine page.
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