Drug interactions
Levonorgestrel + Liraglutide
Severity: Minor
Levonorgestrel and Liraglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Levonorgestrel-containing contraceptives can slightly impair glucose tolerance and may marginally reduce the benefit of liraglutide in diabetic patients. Significant changes are uncommon.
What this interaction means in plain words
Levonorgestrel and Liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Levonorgestrel belongs to Endocrine; Liraglutide belongs to Endocrine.
Why it happens
Possible modest pharmacodynamic antagonism through progestin-related reduction in insulin sensitivity.
What to do
Monitor glycemic control after starting or stopping levonorgestrel. Adjust antidiabetic therapy only if readings change.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Liraglutide
Other interactions of Levonorgestrel
Frequently asked questions
Can I take Levonorgestrel with Liraglutide?
MediHelp rates the interaction as minor. Levonorgestrel and Liraglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Levonorgestrel-containing contraceptives can slightly impair glucose tolerance and may marginally reduce the benefit of liraglutide in diabetic patients. Significant changes are uncommon.
How serious is the interaction between Levonorgestrel and Liraglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glycemic control after starting or stopping levonorgestrel. Adjust antidiabetic therapy only if readings change.
What other medicines interact with Liraglutide?
MediHelp also lists interactions of Liraglutide with, for example, Insulin degludec-liraglutide, Insulin glargine-lixisenatide, Alogliptin-metformin. The full list is on the Liraglutide page.
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