Drug interactions
Levosalbutamol + Propylhexedrine
Severity: Moderate
Levosalbutamol and Propylhexedrine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Propylhexedrine is a sympathomimetic decongestant, and combining it with levosalbutamol may increase heart rate and blood pressure and cause nervousness or palpitations. The effect is mainly relevant in patients with cardiovascular disease.
What this interaction means in plain words
Levosalbutamol and Propylhexedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Levosalbutamol belongs to Respiratory; Propylhexedrine belongs to Respiratory.
Why it happens
Additive sympathomimetic effects from indirect adrenergic release and direct beta-2 agonism.
What to do
Monitor blood pressure and heart rate, and discourage excess decongestant use.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Levosalbutamol
Other interactions of Propylhexedrine
- Isocarboxazid + Propylhexedrine Contraindicated
- Phenelzine + Propylhexedrine Contraindicated
- Linezolid + Propylhexedrine Major
- Propylhexedrine + Selegiline Major
- Propylhexedrine + Tranylcypromine Major
- Adrenaline-articaine + Propylhexedrine Moderate
Frequently asked questions
Can I take Levosalbutamol with Propylhexedrine?
MediHelp rates the interaction as moderate. Levosalbutamol and Propylhexedrine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Propylhexedrine is a sympathomimetic decongestant, and combining it with levosalbutamol may increase heart rate and blood pressure and cause nervousness or palpitations. The effect is mainly relevant in patients with cardiovascular disease.
How serious is the interaction between Levosalbutamol and Propylhexedrine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, and discourage excess decongestant use.
What other medicines interact with Levosalbutamol?
MediHelp also lists interactions of Levosalbutamol with, for example, Amisulpride, Carvedilol, Fexinidazole. The full list is on the Levosalbutamol page.
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