Drug interactions
Liraglutide + Ramipril
Severity: Minor
Liraglutide and Ramipril: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
ACE inhibitors may modestly improve glycemic control and could add to the glucose-lowering effect of liraglutide. The clinical significance is small, since liraglutide alone rarely causes hypoglycemia, but the risk rises if a sulfonylurea or insulin is also used.
What this interaction means in plain words
Liraglutide and Ramipril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Liraglutide belongs to Endocrine; Ramipril belongs to Cardiovascular.
Why it happens
Possible additive glucose lowering through improved insulin sensitivity with ACE inhibition; the mechanism is not firmly established.
What to do
Monitor glycemic control after starting ramipril, and reduce any concurrent sulfonylurea or insulin dose if hypoglycemia appears.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ramipril
- Aliskiren + Ramipril Contraindicated
- Protein a column + Ramipril Contraindicated
- Ramipril + Sacubitril / valsartan Contraindicated
- Ramipril + Sacubitril-valsartan Contraindicated
- Amifostine + Ramipril Major
- Amiloride + Ramipril Major
Other interactions of Liraglutide
Frequently asked questions
Can I take Liraglutide with Ramipril?
MediHelp rates the interaction as minor. Liraglutide and Ramipril have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. ACE inhibitors may modestly improve glycemic control and could add to the glucose-lowering effect of liraglutide. The clinical significance is small, since liraglutide alone rarely causes hypoglycemia, but the risk rises if a sulfonylurea or insulin is also used.
How serious is the interaction between Liraglutide and Ramipril?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor glycemic control after starting ramipril, and reduce any concurrent sulfonylurea or insulin dose if hypoglycemia appears.
What other medicines interact with Ramipril?
MediHelp also lists interactions of Ramipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Ramipril page.
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