Drug interactions
Loratadine + Metoclopramide intranasal
Severity: Minor
Loratadine and Metoclopramide intranasal: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Metoclopramide can cause drowsiness and extrapyramidal effects, while loratadine is minimally sedating. Clinically important interaction is unlikely, though some additive drowsiness is possible.
What this interaction means in plain words
Loratadine and Metoclopramide intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible mild additive CNS effects; no established pharmacokinetic mechanism.
What to do
No specific action is needed beyond counseling about drowsiness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Loratadine
- Acrivastine + Loratadine Moderate
- Amobarbital + Loratadine Moderate
- Fentanyl + Loratadine Moderate
- Isocarboxazid + Loratadine Moderate
- Levoketoconazole + Loratadine Moderate
- Loratadine + Mavacamten Moderate
Frequently asked questions
Can I take Loratadine with Metoclopramide intranasal?
MediHelp rates the interaction as minor. Loratadine and Metoclopramide intranasal have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Metoclopramide can cause drowsiness and extrapyramidal effects, while loratadine is minimally sedating. Clinically important interaction is unlikely, though some additive drowsiness is possible.
How serious is the interaction between Loratadine and Metoclopramide intranasal?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed beyond counseling about drowsiness.
What other medicines interact with Loratadine?
MediHelp also lists interactions of Loratadine with, for example, Acrivastine, Amobarbital, Fentanyl. The full list is on the Loratadine page.
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