Drug interactions
Lorazepam + Teduglutide
Severity: Minor
Lorazepam and Teduglutide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teduglutide improves intestinal fluid and nutrient absorption, which may increase absorption of oral medicines such as lorazepam. This could lead to higher lorazepam exposure and more sedation in some patients.
What this interaction means in plain words
Lorazepam and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lorazepam belongs to Central Nervous System; Teduglutide belongs to Endocrine.
Why it happens
Enhanced intestinal absorption of orally administered drugs due to the intestinotrophic effect of teduglutide.
What to do
Monitor for increased sedation after starting or stopping teduglutide and adjust the lorazepam dose if needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lorazepam
Other interactions of Teduglutide
- Chlordiazepoxide + Teduglutide Moderate
- Clonazepam + Teduglutide Moderate
- Colchicine + Teduglutide Moderate
- Cyclosporin + Teduglutide Moderate
- Digoxin + Teduglutide Moderate
- Ethosuximide + Teduglutide Moderate
Frequently asked questions
Can I take Lorazepam with Teduglutide?
MediHelp rates the interaction as minor. Lorazepam and Teduglutide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Teduglutide improves intestinal fluid and nutrient absorption, which may increase absorption of oral medicines such as lorazepam. This could lead to higher lorazepam exposure and more sedation in some patients.
How serious is the interaction between Lorazepam and Teduglutide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for increased sedation after starting or stopping teduglutide and adjust the lorazepam dose if needed.
What other medicines interact with Lorazepam?
MediHelp also lists interactions of Lorazepam with, for example, Alfentanil, Alprazolam, Amobarbital. The full list is on the Lorazepam page.
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