Drug interactions
Lovastatin + Oxcarbazepine
Severity: Minor
Lovastatin and Oxcarbazepine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oxcarbazepine is a weak CYP3A4 inducer and may modestly reduce lovastatin concentrations. Any loss of lipid-lowering effect is typically small.
What this interaction means in plain words
Lovastatin and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lovastatin belongs to Cardiovascular; Oxcarbazepine belongs to Central Nervous System.
Why it happens
Weak induction of CYP3A4 by oxcarbazepine increases lovastatin metabolism.
What to do
Recheck the lipid profile after the combination is established and adjust the lovastatin dose if control is inadequate.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Lovastatin
- Atazanavir + Lovastatin Contraindicated
- Clarithromycin + Lovastatin Contraindicated
- Cobicistat + Lovastatin Contraindicated
- Conivaptan + Lovastatin Contraindicated
- Darunavir + Lovastatin Contraindicated
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Lovastatin Contraindicated
Other interactions of Oxcarbazepine
- Cabotegravir + Oxcarbazepine Contraindicated
- Oxcarbazepine + Rilpivirine Contraindicated
- Artemether / lumefantrine + Oxcarbazepine Major
- Atazanavir + Oxcarbazepine Major
- Benzhydrocodone / acetaminophen + Oxcarbazepine Major
- Bictegravir + Oxcarbazepine Major
Frequently asked questions
Can I take Lovastatin with Oxcarbazepine?
MediHelp rates the interaction as minor. Lovastatin and Oxcarbazepine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oxcarbazepine is a weak CYP3A4 inducer and may modestly reduce lovastatin concentrations. Any loss of lipid-lowering effect is typically small.
How serious is the interaction between Lovastatin and Oxcarbazepine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Recheck the lipid profile after the combination is established and adjust the lovastatin dose if control is inadequate.
What other medicines interact with Lovastatin?
MediHelp also lists interactions of Lovastatin with, for example, Atazanavir, Clarithromycin, Cobicistat. The full list is on the Lovastatin page.
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