Drug reference
lovastatin
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Drug class
Cardiovascular (Anti Hyperlipidemics)
Mechanism of action
HMG-CoA reductase inhibitor; inhibits the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase
Common side effects
- Flatulence
- Constipation
- CPK elevation
- Abdominal pain
- Diarrhea
Known interactions (11)
- clarithromycin + lovastatin Contraindicated
- erythromycin + lovastatin Contraindicated
- itraconazole + lovastatin Contraindicated
- lovastatin + ritonavir Contraindicated
- aprepitant + lovastatin Major
- fluconazole + lovastatin Major
- dasatinib + lovastatin Moderate
- everolimus + lovastatin Moderate
- fluvoxamine + lovastatin Moderate
- griseofulvin + lovastatin Moderate
- isoniazid + lovastatin Moderate
Related conditions
Frequently asked questions
What drug class is lovastatin?
lovastatin belongs to: Cardiovascular.
How does lovastatin work?
HMG-CoA reductase inhibitor; inhibits the rate-limiting step in cholesterol biosynthesis by competitively inhibiting HMG-CoA reductase
What are the common side effects of lovastatin?
Flatulence, Constipation, CPK elevation, Abdominal pain, Diarrhea
Which drugs interact with lovastatin?
clarithromycin, erythromycin, itraconazole, ritonavir, aprepitant, fluconazole, dasatinib, everolimus, fluvoxamine, griseofulvin, isoniazid
Full monographs, dosing and an interaction checker in the MediHelp app
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