Drug interactions
Loxapine inhaled + Mometasone
Severity: Moderate
Loxapine inhaled and Mometasone: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Inhaled loxapine can cause bronchospasm, particularly in patients with airway disease. Mometasone is used for airway disease, so its use signals a patient at higher risk, rather than a true interaction between the drugs.
What this interaction means in plain words
Loxapine inhaled and Mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
No direct pharmacokinetic or pharmacodynamic interaction is established; risk relates to underlying airway disease.
What to do
Use inhaled loxapine only in patients without active airway disease, and have a short-acting bronchodilator available. Monitor for wheeze or bronchospasm after dosing.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Mometasone
- Mometasone + Ritonavir Major
- Atazanavir + Mometasone Moderate
- Clarithromycin + Mometasone Moderate
- Cobicistat + Mometasone Moderate
- Darunavir + Mometasone Moderate
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Mometasone Moderate
Frequently asked questions
Can I take Loxapine inhaled with Mometasone?
MediHelp rates the interaction as moderate. Loxapine inhaled and Mometasone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Inhaled loxapine can cause bronchospasm, particularly in patients with airway disease. Mometasone is used for airway disease, so its use signals a patient at higher risk, rather than a true interaction between the drugs.
How serious is the interaction between Loxapine inhaled and Mometasone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use inhaled loxapine only in patients without active airway disease, and have a short-acting bronchodilator available. Monitor for wheeze or bronchospasm after dosing.
What other medicines interact with Mometasone?
MediHelp also lists interactions of Mometasone with, for example, Ritonavir, Atazanavir, Clarithromycin. The full list is on the Mometasone page.
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