Drug interactions
Lurasidone + Scopolamine
Severity: Minor
Lurasidone and Scopolamine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lurasidone has minimal anticholinergic activity but can cause somnolence, and scopolamine is sedating and impairs cognition. Combined use may increase drowsiness and psychomotor impairment.
What this interaction means in plain words
Lurasidone and Scopolamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lurasidone belongs to Central Nervous System; Scopolamine belongs to Respiratory.
Why it happens
Additive CNS depressant effects; no significant pharmacokinetic interaction is expected.
What to do
Monitor for excessive sedation or confusion, and counsel patients regarding driving and operating machinery.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Scopolamine
Other interactions of Lurasidone
- Apalutamide + Lurasidone Contraindicated
- Atazanavir + Lurasidone Contraindicated
- Carbamazepine + Lurasidone Contraindicated
- Clarithromycin + Lurasidone Contraindicated
- Cobicistat + Lurasidone Contraindicated
- Conivaptan + Lurasidone Contraindicated
Frequently asked questions
Can I take Lurasidone with Scopolamine?
MediHelp rates the interaction as minor. Lurasidone and Scopolamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lurasidone has minimal anticholinergic activity but can cause somnolence, and scopolamine is sedating and impairs cognition. Combined use may increase drowsiness and psychomotor impairment.
How serious is the interaction between Lurasidone and Scopolamine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for excessive sedation or confusion, and counsel patients regarding driving and operating machinery.
What other medicines interact with Scopolamine?
MediHelp also lists interactions of Scopolamine with, for example, Benzhydrocodone / acetaminophen, Buprenorphine long-acting, Buprenorphine subdermal implant. The full list is on the Scopolamine page.
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