Drug interactions
Magnesium hydroxide + Streptomycin
Severity: Minor
Magnesium hydroxide and Streptomycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Aminoglycosides can cause renal magnesium wasting, leading to hypomagnesemia. Occasional magnesium hydroxide is little affected, but the combination matters little clinically unless magnesium is being given for repletion.
What this interaction means in plain words
Magnesium hydroxide and Streptomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Magnesium hydroxide belongs to Gastrointestinal Tract; Streptomycin belongs to Anti Bacterial.
Why it happens
Aminoglycoside tubular toxicity increases urinary magnesium excretion.
What to do
Monitor serum magnesium, calcium and potassium during prolonged aminoglycoside therapy and replace as needed.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium hydroxide
Other interactions of Streptomycin
Frequently asked questions
Can I take Magnesium hydroxide with Streptomycin?
MediHelp rates the interaction as minor. Magnesium hydroxide and Streptomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Aminoglycosides can cause renal magnesium wasting, leading to hypomagnesemia. Occasional magnesium hydroxide is little affected, but the combination matters little clinically unless magnesium is being given for repletion.
How serious is the interaction between Magnesium hydroxide and Streptomycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium, calcium and potassium during prolonged aminoglycoside therapy and replace as needed.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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