Drug interactions
Magnesium hydroxide + Triamterene
Severity: Minor
Magnesium hydroxide and Triamterene: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Triamterene is potassium-sparing and tends to reduce urinary magnesium loss, which could modestly raise magnesium levels. In renal impairment, regular magnesium hydroxide use could lead to magnesium accumulation.
What this interaction means in plain words
Magnesium hydroxide and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Magnesium hydroxide belongs to Gastrointestinal Tract; Triamterene belongs to Cardiovascular.
Why it happens
Blockade of the epithelial sodium channel reduces renal magnesium excretion.
What to do
No action with normal renal function. Check serum magnesium if renal function is reduced and magnesium products are used regularly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Magnesium hydroxide
Other interactions of Triamterene
- Amiloride + Triamterene Contraindicated
- Eplerenone + Triamterene Contraindicated
- Potassium citrate / citric acid + Triamterene Contraindicated
- Potassium citrate + Triamterene Contraindicated
- Spironolactone + Triamterene Contraindicated
- Aceclofenac + Triamterene Major
Frequently asked questions
Can I take Magnesium hydroxide with Triamterene?
MediHelp rates the interaction as minor. Magnesium hydroxide and Triamterene have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Triamterene is potassium-sparing and tends to reduce urinary magnesium loss, which could modestly raise magnesium levels. In renal impairment, regular magnesium hydroxide use could lead to magnesium accumulation.
How serious is the interaction between Magnesium hydroxide and Triamterene?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action with normal renal function. Check serum magnesium if renal function is reduced and magnesium products are used regularly.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
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