Drug interactions
Measles mumps and rubella vaccine live + Tetanus immune globulin
Severity: Minor
Measles mumps and rubella vaccine live and Tetanus immune globulin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetanus immune globulin contains little antibody to these viruses, so any effect on the live vaccine response is expected to be minimal.
What this interaction means in plain words
Measles mumps and rubella vaccine live and Tetanus immune globulin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Theoretical neutralization of live vaccine virus by passively acquired antibody.
What to do
No routine delay is required for TIG. Check serology or revaccinate if immunity is in doubt.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Tetanus immune globulin
- Efgartigimod / hyaluronidase sc + Tetanus immune globulin Moderate
- Efgartigimod alfa + Tetanus immune globulin Moderate
- Rozanolixizumab + Tetanus immune globulin Moderate
- Tetanus immune globulin + Varicella virus vaccine live Moderate
- Measles mumps and rubella vaccine + Tetanus immune globulin Minor
- Measles mumps rubella and varicella vaccine live + Tetanus immune globulin Minor
Frequently asked questions
Can I take Measles mumps and rubella vaccine live with Tetanus immune globulin?
MediHelp rates the interaction as minor. Measles mumps and rubella vaccine live and Tetanus immune globulin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tetanus immune globulin contains little antibody to these viruses, so any effect on the live vaccine response is expected to be minimal.
How serious is the interaction between Measles mumps and rubella vaccine live and Tetanus immune globulin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine delay is required for TIG. Check serology or revaccinate if immunity is in doubt.
What other medicines interact with Tetanus immune globulin?
MediHelp also lists interactions of Tetanus immune globulin with, for example, Efgartigimod / hyaluronidase sc, Efgartigimod alfa, Rozanolixizumab. The full list is on the Tetanus immune globulin page.
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