Drug interactions
Mefloquine + Timolol
Severity: Minor
Mefloquine and Timolol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mefloquine can cause bradycardia, and systemic timolol also slows heart rate and AV conduction. Combined use may cause additive bradycardia or conduction block, especially with oral timolol or eye drops in susceptible patients.
What this interaction means in plain words
Mefloquine and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Mefloquine belongs to Anti Parasitic; Timolol belongs to Cardiovascular.
Why it happens
Additive effects on cardiac conduction; a metabolic interaction is not established.
What to do
Monitor heart rate in patients on timolol who start mefloquine. Reassess therapy if symptomatic bradycardia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Mefloquine and Timolol, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Mefloquine
- Arsenic trioxide + Mefloquine Contraindicated
- Dronedarone + Mefloquine Contraindicated
- Ibutilide + Mefloquine Contraindicated
- Levoketoconazole + Mefloquine Contraindicated
- Mefloquine + Nilotinib Contraindicated
- Mefloquine + Pimozide Contraindicated
Other interactions of Timolol
- Acebutolol + Timolol Major
- Albuterol + Timolol Major
- Aldesleukin + Timolol Major
- Amifostine + Timolol Major
- Amiodarone + Timolol Major
- Arformoterol + Timolol Major
Frequently asked questions
Can I take Mefloquine with Timolol?
MediHelp rates the interaction as minor. Mefloquine and Timolol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Mefloquine can cause bradycardia, and systemic timolol also slows heart rate and AV conduction. Combined use may cause additive bradycardia or conduction block, especially with oral timolol or eye drops in susceptible patients.
How serious is the interaction between Mefloquine and Timolol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate in patients on timolol who start mefloquine. Reassess therapy if symptomatic bradycardia occurs.
What other medicines interact with Mefloquine?
MediHelp also lists interactions of Mefloquine with, for example, Arsenic trioxide, Dronedarone, Ibutilide. The full list is on the Mefloquine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
