Skip to content

Drug interactions

Meprobamate + Methamphetamine

Severity: Minor

Meprobamate and Methamphetamine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Meprobamate is a sedative-anxiolytic and methamphetamine is a stimulant. The stimulant may mask sedation and each drug may blunt the intended effect of the other.

What this interaction means in plain words

Meprobamate and Methamphetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Opposing CNS pharmacodynamic effects; no established pharmacokinetic interaction.

What to do

Counsel on residual impairment despite apparent alertness. Review the indication for each drug if they seem to be counteracting one another.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+ members

Unlock the full page

Create an account and start a Pro+ trial to unlock the full management advice for Meprobamate and Methamphetamine, the additional notes, the evidence detail and the whole-prescription interaction checker.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Try Pro+ free for 7 days on the web. No card needed.

Frequently asked questions

Can I take Meprobamate with Methamphetamine?

MediHelp rates the interaction as minor. Meprobamate and Methamphetamine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Meprobamate is a sedative-anxiolytic and methamphetamine is a stimulant. The stimulant may mask sedation and each drug may blunt the intended effect of the other.

How serious is the interaction between Meprobamate and Methamphetamine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel on residual impairment despite apparent alertness. Review the indication for each drug if they seem to be counteracting one another.

What other medicines interact with Methamphetamine?

MediHelp also lists interactions of Methamphetamine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Methamphetamine page.

Full monographs, dosing and an interaction checker in the MediHelp app

Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.

Browse A–Z · Drug interactions

Get the app Sign in