Drug interactions
Mesalamine + Verapamil
Severity: Minor
Mesalamine and Verapamil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Verapamil has mild antiplatelet effects and mesalamine has been rarely associated with platelet effects. No meaningful clinical interaction is established.
What this interaction means in plain words
Mesalamine and Verapamil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Mesalamine belongs to Gastrointestinal Tract; Verapamil belongs to Cardiovascular.
Why it happens
Mechanism is not established; any additive antiplatelet effect is theoretical.
What to do
No specific action is needed. Monitor for unusual bruising or bleeding if other antiplatelet agents are used.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mesalamine
Other interactions of Verapamil
- Dofetilide + Verapamil Contraindicated
- Flibanserin + Verapamil Contraindicated
- Lomitapide + Verapamil Contraindicated
- Lonafarnib + Verapamil Contraindicated
- Pimozide + Verapamil Contraindicated
- Acebutolol + Verapamil Major
Frequently asked questions
Can I take Mesalamine with Verapamil?
MediHelp rates the interaction as minor. Mesalamine and Verapamil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Verapamil has mild antiplatelet effects and mesalamine has been rarely associated with platelet effects. No meaningful clinical interaction is established.
How serious is the interaction between Mesalamine and Verapamil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed. Monitor for unusual bruising or bleeding if other antiplatelet agents are used.
What other medicines interact with Mesalamine?
MediHelp also lists interactions of Mesalamine with, for example, Measles mumps rubella and varicella vaccine live, Varicella virus vaccine live, Aceclofenac. The full list is on the Mesalamine page.
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