Drug interactions
Mesterolone + Metformin-repaglinide
Severity: Minor
Mesterolone and Metformin-repaglinide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Androgens can improve insulin sensitivity and may enhance the glucose-lowering effect of antidiabetic drugs. This could increase the risk of hypoglycemia with repaglinide, although the effect is usually small.
What this interaction means in plain words
Mesterolone and Metformin-repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Mesterolone belongs to Endocrine; Metformin-repaglinide belongs to Endocrine.
Why it happens
Possible additive effect on insulin sensitivity and glucose metabolism.
What to do
Monitor blood glucose when mesterolone is started and reduce the repaglinide dose if hypoglycemia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Metformin-repaglinide
Other interactions of Mesterolone
Frequently asked questions
Can I take Mesterolone with Metformin-repaglinide?
MediHelp rates the interaction as minor. Mesterolone and Metformin-repaglinide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Androgens can improve insulin sensitivity and may enhance the glucose-lowering effect of antidiabetic drugs. This could increase the risk of hypoglycemia with repaglinide, although the effect is usually small.
How serious is the interaction between Mesterolone and Metformin-repaglinide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose when mesterolone is started and reduce the repaglinide dose if hypoglycemia occurs.
What other medicines interact with Metformin-repaglinide?
MediHelp also lists interactions of Metformin-repaglinide with, for example, Gemfibrozil, Apalutamide, Clarithromycin. The full list is on the Metformin-repaglinide page.
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