Drug interactions
Mesterolone + Prednisolone
Severity: Minor
Mesterolone and Prednisolone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both androgens and corticosteroids can cause sodium and fluid retention, so combined use may increase edema. Patients with heart, kidney or liver disease are at higher risk.
What this interaction means in plain words
Mesterolone and Prednisolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Mesterolone belongs to Endocrine; Prednisolone belongs to Endocrine.
Why it happens
Additive sodium and water retention from corticosteroid mineralocorticoid effects and androgen effects.
What to do
Monitor weight, edema and blood pressure, especially in patients with cardiac or renal disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Prednisolone
- Bcg vaccine live + Prednisolone Contraindicated
- Measles mumps and rubella vaccine live + Prednisolone Contraindicated
- Measles mumps rubella and varicella vaccine live + Prednisolone Contraindicated
- Measles vaccine + Prednisolone Contraindicated
- Mifepristone + Prednisolone Contraindicated
- Prednisolone + Radium-223 dichloride Contraindicated
Other interactions of Mesterolone
Frequently asked questions
Can I take Mesterolone with Prednisolone?
MediHelp rates the interaction as minor. Mesterolone and Prednisolone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both androgens and corticosteroids can cause sodium and fluid retention, so combined use may increase edema. Patients with heart, kidney or liver disease are at higher risk.
How serious is the interaction between Mesterolone and Prednisolone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor weight, edema and blood pressure, especially in patients with cardiac or renal disease.
What other medicines interact with Prednisolone?
MediHelp also lists interactions of Prednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Prednisolone page.
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