Drug interactions
Metaproterenol + Modafinil
Severity: Minor
Metaproterenol and Modafinil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Metaproterenol is a beta-agonist that can cause tremor, tachycardia and nervousness. Combined with modafinil, additive stimulation may cause anxiety, insomnia and palpitations.
What this interaction means in plain words
Metaproterenol and Modafinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Additive sympathomimetic and CNS stimulant effects.
What to do
Monitor heart rate, blood pressure and symptoms of nervousness, especially in patients with heart disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Modafinil
Frequently asked questions
Can I take Metaproterenol with Modafinil?
MediHelp rates the interaction as minor. Metaproterenol and Modafinil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Metaproterenol is a beta-agonist that can cause tremor, tachycardia and nervousness. Combined with modafinil, additive stimulation may cause anxiety, insomnia and palpitations.
How serious is the interaction between Metaproterenol and Modafinil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate, blood pressure and symptoms of nervousness, especially in patients with heart disease.
What other medicines interact with Modafinil?
MediHelp also lists interactions of Modafinil with, for example, Lenacapavir, Leniolisib, Lorlatinib. The full list is on the Modafinil page.
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