Drug interactions
Metaproterenol + Trazodone
Severity: Minor
Metaproterenol and Trazodone: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both agents can affect heart rate and blood pressure, and beta-agonists may cause tachycardia and hypokalemia. The effect is usually modest, and the tricyclic mechanism cited historically does not clearly apply to trazodone.
What this interaction means in plain words
Metaproterenol and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive cardiovascular effects; no well-established specific mechanism for trazodone.
What to do
No routine change is needed; monitor heart rate and palpitations in patients with cardiac disease.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Trazodone
- Arsenic trioxide + Trazodone Contraindicated
- Ibutilide + Trazodone Contraindicated
- Isocarboxazid + Trazodone Contraindicated
- Levoketoconazole + Trazodone Contraindicated
- Methylene blue + Trazodone Contraindicated
- Phenelzine + Trazodone Contraindicated
Frequently asked questions
Can I take Metaproterenol with Trazodone?
MediHelp rates the interaction as minor. Metaproterenol and Trazodone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Both agents can affect heart rate and blood pressure, and beta-agonists may cause tachycardia and hypokalemia. The effect is usually modest, and the tricyclic mechanism cited historically does not clearly apply to trazodone.
How serious is the interaction between Metaproterenol and Trazodone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine change is needed; monitor heart rate and palpitations in patients with cardiac disease.
What other medicines interact with Trazodone?
MediHelp also lists interactions of Trazodone with, for example, Arsenic trioxide, Ibutilide, Isocarboxazid. The full list is on the Trazodone page.
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