Drug interactions
Methamphetamine + Opium tincture
Severity: Moderate
Methamphetamine and Opium tincture: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Opium tincture contains morphine and causes sedation and respiratory depression, whereas methamphetamine is a stimulant. The stimulant may mask opioid sedation, creating a risk of overdose when its effect wanes.
What this interaction means in plain words
Methamphetamine and Opium tincture can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Opposing CNS pharmacodynamic effects, with the stimulant masking opioid-induced sedation.
What to do
Monitor respiratory rate and level of consciousness, and do not rely on alertness alone. Use the lowest effective opioid dose and counsel the patient on overdose risk.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Methamphetamine
- Isocarboxazid + Methamphetamine Contraindicated
- Linezolid + Methamphetamine Contraindicated
- Methamphetamine + Phenelzine Contraindicated
- Methamphetamine + Procarbazine Contraindicated
- Methamphetamine + Rasagiline Contraindicated
- Methamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Methamphetamine with Opium tincture?
MediHelp rates the interaction as moderate. Methamphetamine and Opium tincture can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Opium tincture contains morphine and causes sedation and respiratory depression, whereas methamphetamine is a stimulant. The stimulant may mask opioid sedation, creating a risk of overdose when its effect wanes.
How serious is the interaction between Methamphetamine and Opium tincture?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor respiratory rate and level of consciousness, and do not rely on alertness alone. Use the lowest effective opioid dose and counsel the patient on overdose risk.
What other medicines interact with Methamphetamine?
MediHelp also lists interactions of Methamphetamine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Methamphetamine page.
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