Drug interactions
Methamphetamine + Quazepam
Severity: Minor
Methamphetamine and Quazepam: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Quazepam is a long-acting benzodiazepine hypnotic and methamphetamine is a stimulant, so their effects on arousal oppose each other. Stimulant effects can mask sedation without reducing the psychomotor impairment caused by the benzodiazepine.
What this interaction means in plain words
Methamphetamine and Quazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Opposing pharmacodynamic effects: GABA-A potentiation versus catecholamine release.
What to do
No routine dose change is needed. Advise the patient that impairment may persist even if they feel alert.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Methamphetamine
- Isocarboxazid + Methamphetamine Contraindicated
- Linezolid + Methamphetamine Contraindicated
- Methamphetamine + Phenelzine Contraindicated
- Methamphetamine + Procarbazine Contraindicated
- Methamphetamine + Rasagiline Contraindicated
- Methamphetamine + Safinamide Contraindicated
Frequently asked questions
Can I take Methamphetamine with Quazepam?
MediHelp rates the interaction as minor. Methamphetamine and Quazepam have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Quazepam is a long-acting benzodiazepine hypnotic and methamphetamine is a stimulant, so their effects on arousal oppose each other. Stimulant effects can mask sedation without reducing the psychomotor impairment caused by the benzodiazepine.
How serious is the interaction between Methamphetamine and Quazepam?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed. Advise the patient that impairment may persist even if they feel alert.
What other medicines interact with Methamphetamine?
MediHelp also lists interactions of Methamphetamine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Methamphetamine page.
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