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Drug interactions

Methamphetamine + Yerba mate

Severity: Minor

Methamphetamine and Yerba mate: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Yerba mate contains caffeine and other methylxanthines with stimulant activity. Combined with methamphetamine it may increase cardiovascular stimulation, nervousness and sleep disturbance.

What this interaction means in plain words

Methamphetamine and Yerba mate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Evidence level: Low

Why it happens

Additive sympathomimetic and CNS stimulant effects of methylxanthines with methamphetamine.

What to do

Advise limiting yerba mate and other caffeine sources. Monitor blood pressure and heart rate if consumed regularly.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Methamphetamine with Yerba mate?

MediHelp rates the interaction as minor. Methamphetamine and Yerba mate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Yerba mate contains caffeine and other methylxanthines with stimulant activity. Combined with methamphetamine it may increase cardiovascular stimulation, nervousness and sleep disturbance.

How serious is the interaction between Methamphetamine and Yerba mate?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Advise limiting yerba mate and other caffeine sources. Monitor blood pressure and heart rate if consumed regularly.

What other medicines interact with Methamphetamine?

MediHelp also lists interactions of Methamphetamine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Methamphetamine page.

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