Drug interactions
Microbiota + Tigecycline
Severity: Moderate
Microbiota and Tigecycline: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral fecal microbiota spore products depend on viable bacterial spores to repopulate the gut. Antibiotics given close to dosing may reduce engraftment and therapeutic effect.
What this interaction means in plain words
Microbiota and Tigecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Why it happens
Antibacterial activity against the administered microbiota reduces engraftment.
What to do
Complete antibiotic therapy before starting the microbiota product, allowing the interval stated in the product labeling.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Tigecycline
Frequently asked questions
Can I take Microbiota with Tigecycline?
MediHelp rates the interaction as moderate. Microbiota and Tigecycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral fecal microbiota spore products depend on viable bacterial spores to repopulate the gut. Antibiotics given close to dosing may reduce engraftment and therapeutic effect.
How serious is the interaction between Microbiota and Tigecycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete antibiotic therapy before starting the microbiota product, allowing the interval stated in the product labeling.
What other medicines interact with Tigecycline?
MediHelp also lists interactions of Tigecycline with, for example, Typhoid vaccine live, Bcg vaccine live, Cholera vaccine. The full list is on the Tigecycline page.
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