Drug interactions
Mipomersen + Mirtazapine
Severity: Minor
Mipomersen and Mirtazapine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Mipomersen is associated with hepatotoxicity and raised transaminases, and mirtazapine can occasionally raise liver enzymes. The overlap is theoretical, and no distinct pharmacokinetic interaction is established.
What this interaction means in plain words
Mipomersen and Mirtazapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Why it happens
Possible additive hepatotoxicity; not well established.
What to do
Monitor liver enzymes as required for mipomersen and investigate any rise.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mirtazapine
- Isocarboxazid + Mirtazapine Contraindicated
- Mirtazapine + Phenelzine Contraindicated
- Mirtazapine + Pimozide Contraindicated
- Mirtazapine + Procarbazine Contraindicated
- Mirtazapine + Rasagiline Contraindicated
- Mirtazapine + Selegiline Contraindicated
Frequently asked questions
Can I take Mipomersen with Mirtazapine?
MediHelp rates the interaction as minor. Mipomersen and Mirtazapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Mipomersen is associated with hepatotoxicity and raised transaminases, and mirtazapine can occasionally raise liver enzymes. The overlap is theoretical, and no distinct pharmacokinetic interaction is established.
How serious is the interaction between Mipomersen and Mirtazapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor liver enzymes as required for mipomersen and investigate any rise.
What other medicines interact with Mirtazapine?
MediHelp also lists interactions of Mirtazapine with, for example, Isocarboxazid, Phenelzine, Pimozide. The full list is on the Mirtazapine page.
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