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Drug interactions

Moexipril + Potassium iodide

Severity: Moderate

Moexipril and Potassium iodide: moderate interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Potassium iodide supplies a potassium load, and ACE inhibitors reduce renal potassium excretion. Hyperkalemia is possible, especially with renal impairment, with prolonged or high-dose iodide.

What this interaction means in plain words

Moexipril and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Moexipril belongs to Cardiovascular; Potassium iodide belongs to Endocrine.

Evidence level: Moderate

Why it happens

ACE inhibition lowers aldosterone and potassium excretion, adding to potassium from the iodide salt.

What to do

Monitor serum potassium and renal function with prolonged or repeated potassium iodide use.

What to ask your pharmacist

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Moexipril with Potassium iodide?

MediHelp rates the interaction as moderate. Moexipril and Potassium iodide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Potassium iodide supplies a potassium load, and ACE inhibitors reduce renal potassium excretion. Hyperkalemia is possible, especially with renal impairment, with prolonged or high-dose iodide.

How serious is the interaction between Moexipril and Potassium iodide?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium and renal function with prolonged or repeated potassium iodide use.

What other medicines interact with Moexipril?

MediHelp also lists interactions of Moexipril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Moexipril page.

Full monographs, dosing and an interaction checker in the MediHelp app

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