Drug interactions
Moxifloxacin + Telavancin
Severity: Major
Moxifloxacin and Telavancin: major interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxifloxacin is a well-known QTc-prolonging fluoroquinolone, and telavancin can also lengthen the QTc. Combined use may increase the risk of torsades de pointes.
What this interaction means in plain words
Moxifloxacin and Telavancin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Moxifloxacin belongs to Anti Bacterial; Telavancin belongs to Anti Bacterial.
Why it happens
Additive prolongation of ventricular repolarization via potassium channel blockade.
What to do
Avoid combining them when another antibiotic can be used. If needed, monitor ECG and electrolytes and correct any deficits.
What to ask your pharmacist
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Other interactions of Telavancin
- Telavancin + Thioridazine Contraindicated
- Adagrasib + Telavancin Major
- Amiodarone + Telavancin Major
- Amisulpride + Telavancin Major
- Anagrelide + Telavancin Major
- Arsenic trioxide + Telavancin Major
Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Frequently asked questions
Can I take Moxifloxacin with Telavancin?
MediHelp rates the interaction as major. Moxifloxacin and Telavancin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Moxifloxacin is a well-known QTc-prolonging fluoroquinolone, and telavancin can also lengthen the QTc. Combined use may increase the risk of torsades de pointes.
How serious is the interaction between Moxifloxacin and Telavancin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combining them when another antibiotic can be used. If needed, monitor ECG and electrolytes and correct any deficits.
What other medicines interact with Telavancin?
MediHelp also lists interactions of Telavancin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Telavancin page.
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