Drug interactions
Mycophenolate mofetil + Trastuzumab
Severity: Minor
Mycophenolate mofetil and Trastuzumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Trastuzumab is not itself strongly immunosuppressive, but it can increase neutropenia when given with myelosuppressive agents. Combined with mycophenolate, which can cause leukopenia, it may modestly raise the risk of infection.
What this interaction means in plain words
Mycophenolate mofetil and Trastuzumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Mycophenolate mofetil belongs to Miscellaneous; Trastuzumab belongs to Oncology.
Why it happens
Possible additive neutropenia; no direct pharmacokinetic interaction is established.
What to do
Monitor complete blood counts and signs of infection during combined therapy. Reduce or hold mycophenolate if significant neutropenia occurs.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Mycophenolate mofetil and Trastuzumab, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contraindicated
- Bcg vaccine live + Mycophenolate mofetil Contraindicated
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contraindicated
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contraindicated
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contraindicated
- Measles vaccine + Mycophenolate mofetil Contraindicated
Other interactions of Trastuzumab
Frequently asked questions
Can I take Mycophenolate mofetil with Trastuzumab?
MediHelp rates the interaction as minor. Mycophenolate mofetil and Trastuzumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Trastuzumab is not itself strongly immunosuppressive, but it can increase neutropenia when given with myelosuppressive agents. Combined with mycophenolate, which can cause leukopenia, it may modestly raise the risk of infection.
How serious is the interaction between Mycophenolate mofetil and Trastuzumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor complete blood counts and signs of infection during combined therapy. Reduce or hold mycophenolate if significant neutropenia occurs.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
