Drug interactions
Nadolol + Sarecycline
Severity: Minor
Nadolol and Sarecycline: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Nadolol is a P-glycoprotein substrate, and inhibition of this transporter could in theory raise its levels. The clinical significance of sarecycline in this respect is not well established.
What this interaction means in plain words
Nadolol and Sarecycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Nadolol belongs to Cardiovascular; Sarecycline belongs to Anti Bacterial.
Why it happens
Possible P-glycoprotein inhibition by sarecycline that could increase nadolol exposure; this is predicted and not firmly established.
What to do
No routine adjustment is needed. Monitor heart rate and blood pressure for signs of excess beta-blockade when starting sarecycline.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Nadolol
- Acebutolol + Nadolol Major
- Adrenaline-articaine + Nadolol Major
- Albuterol + Nadolol Major
- Amifostine + Nadolol Major
- Amiodarone + Nadolol Major
- Arformoterol + Nadolol Major
Other interactions of Sarecycline
- Acitretin + Sarecycline Contraindicated
- Isotretinoin + Sarecycline Major
- Sarecycline + Tretinoin Major
- Aluminum hydroxide + Sarecycline Moderate
- Calcium carbonate + Sarecycline Moderate
- Calcium + Sarecycline Moderate
Frequently asked questions
Can I take Nadolol with Sarecycline?
MediHelp rates the interaction as minor. Nadolol and Sarecycline have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nadolol is a P-glycoprotein substrate, and inhibition of this transporter could in theory raise its levels. The clinical significance of sarecycline in this respect is not well established.
How serious is the interaction between Nadolol and Sarecycline?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is needed. Monitor heart rate and blood pressure for signs of excess beta-blockade when starting sarecycline.
What other medicines interact with Nadolol?
MediHelp also lists interactions of Nadolol with, for example, Acebutolol, Adrenaline-articaine, Albuterol. The full list is on the Nadolol page.
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