Drug interactions
Nebivolol + Nimodipine
Severity: Moderate
Nebivolol and Nimodipine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Both lower blood pressure, so combining them can lead to excessive hypotension. This is particularly relevant when nimodipine is used after subarachnoid hemorrhage, where maintaining cerebral perfusion matters.
What this interaction means in plain words
Nebivolol and Nimodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Nebivolol belongs to Cardiovascular; Nimodipine belongs to Cardiovascular.
Why it happens
Additive hypotensive effects of beta-blockade and calcium channel blockade.
What to do
Monitor blood pressure closely and adjust or hold nebivolol if hypotension occurs. Check heart rate as well.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Nebivolol
- Acebutolol + Nebivolol Major
- Aldesleukin + Nebivolol Major
- Amiodarone + Nebivolol Major
- Atenolol-chlorthalidone + Nebivolol Major
- Atenolol + Nebivolol Major
- Betaxolol + Nebivolol Major
Other interactions of Nimodipine
- Apalutamide + Nimodipine Major
- Carbamazepine + Nimodipine Major
- Ceritinib + Nimodipine Major
- Clarithromycin + Nimodipine Major
- Cobicistat + Nimodipine Major
- Darunavir + Nimodipine Major
Frequently asked questions
Can I take Nebivolol with Nimodipine?
MediHelp rates the interaction as moderate. Nebivolol and Nimodipine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both lower blood pressure, so combining them can lead to excessive hypotension. This is particularly relevant when nimodipine is used after subarachnoid hemorrhage, where maintaining cerebral perfusion matters.
How serious is the interaction between Nebivolol and Nimodipine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure closely and adjust or hold nebivolol if hypotension occurs. Check heart rate as well.
What other medicines interact with Nebivolol?
MediHelp also lists interactions of Nebivolol with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Nebivolol page.
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